Predicting Micro-Hardness of Post-Treated Hydroxyapatite Layer Using Surface Response Methodology

Maryam Tamizi, S. Izman, Mostafa Rezazadeh Shirdar, Nabeel Najm Al-Mayyahi, Sadegh Parhizkar


Micro-hardness of sol-gel-derived hydroxyapatite (HA) coating layer on Ti-13Nb-13Zr in different sintering conditions was investigated. Sintering post-treatment of coated samples was carried out based on full factorial design followed by surface response methodology. Analysis of variance (ANOVA) indicates that the sintering temperature is a more significant factor rather than sintering time in determining the Micro-hardness of the HA coating layer. Based on experiments results a mathematical model was created in order to be used for prediction of Micro-harness value in different sintering conditions. The validity of the generated model by Response Surface Methodology was confirmed through comparing the predicted values and experimental results and the close agreement was observed.


Ti-13Nb-13Zr, Sol-gel, hydroxyapatite, Micro-hardness, Response surface methodology

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