Adaptive Neuro-Fuzzy Inference System (ANFIS) in Parkinson’s Disease (PD) Diagnosis
Abstract
Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by motor impairments such as tremors, rigidity, and bradykinesia, along with a wide range of non-motor symptoms. Conventional diagnostic methods rely primarily on clinical evaluation, often leading to delayed or inaccurate diagnoses due to overlapping symptoms with other movement disorders. The integration of Artificial Intelligence (AI) in medical practice has opened new pathways for improving diagnostic accuracy and early detection of PD. Among these approaches, the Adaptive Neuro-Fuzzy Inference System (ANFIS) has gained attention for its ability to combine the adaptive learning power of neural networks with the uncertainty-handling capacity of fuzzy logic. ANFIS models have been applied to diverse patient data sources, including speech analysis, gait dynamics, handwriting patterns, and biomedical signals, to differentiate PD from healthy controls and assess disease severity. This paper reviews the role of ANFIS in PD diagnosis, highlighting its advantages over conventional machine learning models, its medical implications, challenges, and future research opportunities.
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